Study Finds Why Women Are More Vulnerable To Migraines

A new study has found the reason, why females are more vulnerable to migraines and other certain stress-related and allergic diseases and concluded that this is because of the distinct differences found in mast cells, a type of white blood cell that is part of the immune system. Mast cells play a key role in stress-related health issues that are typically more common in women.The study was published in the journal Biology of Sex Differences.Mast cells play a prominent role in such issues The stress-related health issues, which are common in women include allergic disorders, auto-immune diseases, migraines and irritable bowel syndrome (IBS) and since mast cells play a prominent role in such issues, they are an important category of immune cells. The genes act vary immensely between the sexes “Over 8,000 differentially expressed genes were found in female mast cells compared to male mast cells,” said lead researcher Adam Moeser, associate professor at Michigan State University, US. “While male and female mast cells have the same sets of genes on their chromosomes, with the exception of the XY sex chromosomes, the way the genes act vary immensely between the sexes,” Moeser noted.May create a more aggressive response RNA genome is a primary building block in all forms of life and a further in-depth analysis of the genes within this revealed an increase in activity related to the production and storage of inflammatory substances. These substances can create a more aggressive response in the body and result in disease. Scientists could develop new sex-specific treatments “This could explain why women, or men, are more or less vulnerable to certain types of diseases,” Moeser said adding "Scientists, with this new understanding of how different genes act, could eventually develop new sex-specific treatments that target these immune cells and stop the onset of disease."

Study Finds Why Women Are More Vulnerable To Migraines